Table 2.
Comparison of CA-125 and neutrophil to lymphocyte ratio (NLR) among underweight, normal to overweight, and obesity patients according to the treatment time.
| BMI |
CA-125 (median, U/mL) |
NLR (median) |
Confounding factors | |||
|---|---|---|---|---|---|---|
| Stage IV disease | Grade 3 disease | Nonserous histology | Suboptimal debulking | |||
| At diagnosis | ||||||
| Underweight | 185.5 | 8∗,† | 1 (8.3)∗,† | 3 (25.0)∗,† | 4 (33.3)∗,† | 2 (16.7)∗ |
| Normal to overweight | 865∗ | 9∗,‡ | 69 (22.3)∗,‡ | 156 (50.3)∗,‡ | 69 (22.3)∗,‡ | 149 (48.1)∗,† |
| Obesity | 912.5∗ | 6.75†,‡ | 5 (13.9)†,‡ | 21 (58.3)†,‡ | 5 (13.9)†,‡ | 21 (58.3)† |
| P value | 0.04 | 0.47 | 0.28 | 0.14 | 0.33 | 0.04 |
| After surgery | ||||||
| Underweight | 95.6∗,† | 2.58∗,† | 6 (18.8)∗,† | 15 (46.9)∗,† | 3 (9.4)∗,† | 10 (32.2)∗,† |
| Normal to overweight | 190.0∗,‡ | 2.67∗,‡ | 65 (22.3)∗,‡ | 146 (50)∗,‡ | 67 (22.9)∗,‡ | 143 (49)∗,‡ |
| Obesity | 87.5†,‡ | 3.14†,‡ | 5 (18.5)†,‡ | 16 (59.3)†,‡ | 5 (17.9)†,‡ | 16 (59.3)†,‡ |
| P value | 0.78 | 0.23 | 0.83 | 0.60 | 0.29 | 0.08 |
| After treatment | ||||||
| Underweight | 8∗,† | 2.15∗ | 5 (17.2)∗,† | 13 (44.8)∗,† | 6 (20.7)∗,† | 10 (34.5)∗,† |
| Normal to overweight | 9∗,‡ | 1.56∗,† | 62 (20.7)∗,‡ | 148 (50.7)∗,‡ | 67 (22.4)∗,‡ | 146 (48.8)∗,‡ |
| Obesity | 6.8†,‡ | 1.47† | 8 (28.6)†,‡ | 18 (66.7)†,‡ | 4 (14.3)†,‡ | 13 (46.4)†,‡ |
| P value | 0.21 | 0.09 | 0.54 | 0.27 | 0.60 | 0.33 |
BMI: body mass index; ∗,†,‡no significant difference between two groups with the same symbol.