. 2014 Jun 5;10(2):585–592. doi: 10.3892/mmr.2014.2302

Table IV.

Parameters of the in vivo HCC models following treatment with FK506 and NS.

Parameters	NS	FK506	P
Tumor weight (g)^a	15.56±11.17	28.19±3.89	0.041^c
Ascite fluid (ml)^a	13.13±21.87	21.25±6.94	0.317
Lymph node metastasis^b	0	8	0.002^c
Abdominal wall metastasis^b	2	5	0.442
Pulmonary nodules (n)^a	1.39±1.25	6.50±4.63	0.012^c
Expression of CXCR4^a	1.48±0.29	2.50±0.62	0.048^c
Expression of SDF-1α^a	1.46±0.39	2.54±0.94	0.026^c

Normally distributed data, expressed as mean ± SD;

distribution of data was not normal, median values shown;

P<0.05, compared to the NS group.

HCC, hepatocellular carcinoma; NS, normal saline; FK506, tacrolimus; CXCR4, C-X-C chemokine receptor type 4; SDF-1α, stromal cell-derived factor-1α.