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. 2014 Jun 2;10(2):615–624. doi: 10.3892/mmr.2014.2292

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Copyright © 2014, Spandidos Publications

This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.

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Effects of NAC on myocardial cell apoptosis in heart failure. (A) The apoptotic index was determined using the TUNEL assay. Pair-wise multiple comparisons between groups were determined using Bonferroni’s test with α=0.017 adjustment. ^*P<0.05 indicates a statistically significant difference between the indicated group and the control group; ^†P<0.05 indicates a statistically significant difference between the indicated group and the HF group. (B) Representative images of the TUNEL analysis from each group are demonstrated (magnification, ×400). NAC, N-acetylcysteine; HF group, untreated heart failure group; TUNEL, Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling.