Table 2.
Risk of Hematological Malignancies among Individuals with AUDs.
Disease |
Men |
Women |
All |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
O | SIR | 95% CI | O | SIR | 95% CI | O | SIR | 95% CI | ||||
Non-Hodgkin lymphoma | 791 | 0.64 | 0.60 | 0.69 | 150 | 0.69 | 0.58 | 0.81 | 941 | 0.65 | 0.61 | 0.69 |
Diffuse large B cell | 107 | 0.83 | 0.68 | 1.01 | 24 | 0.98 | 0.62 | 1.45 | 131 | 0.86 | 0.72 | 1.02 |
Follicular | 48 | 0.72 | 0.53 | 0.96 | 14 | 0.72 | 0.39 | 1.21 | 62 | 0.72 | 0.55 | 0.93 |
Hodgkin disease | 184 | 0.70 | 0.60 | 0.81 | 41 | 0.77 | 0.55 | 1.04 | 225 | 0.71 | 0.62 | 0.81 |
Mixed cellularity classic | 15 | 0.86 | 0.48 | 1.42 | 3 | 1.18 | 0.22 | 3.49 | 18 | 0.90 | 0.53 | 1.43 |
Nodular sclerosis classic | 58 | 1.27 | 0.96 | 1.64 | 12 | 0.76 | 0.39 | 1.33 | 70 | 1.14 | 0.89 | 1.44 |
Myeloma | 167 | 0.53 | 0.45 | 0.61 | 29 | 0.49 | 0.33 | 0.70 | 196 | 0.52 | 0.45 | 0.60 |
Leukemia | 325 | 0.52 | 0.46 | 0.58 | 68 | 0.46 | 0.36 | 0.59 | 393 | 0.51 | 0.46 | 0.56 |
Acute lymphatic leukemia | 55 | 0.49 | 0.37 | 0.63 | 17 | 0.57 | 0.33 | 0.91 | 72 | 0.50 | 0.39 | 0.63 |
Acute myeloid leukemia | 54 | 0.31 | 0.24 | 0.41 | 9 | 0.21 | 0.09 | 0.39 | 63 | 0.29 | 0.22 | 0.37 |
Chronic myeloid leukemia | 52 | 0.53 | 0.40 | 0.70 | 11 | 0.58 | 0.29 | 1.04 | 63 | 0.54 | 0.41 | 0.69 |
All | 1467 | 0.60 | 0.57 | 0.63 | 288 | 0.60 | 0.54 | 0.68 | 1755 | 0.60 | 0.57 | 0.63 |
O, observed number of cases; SIR, standardized incidence ratio; CI, confidence interval.
Bold type, 95% CI does not include 1.00.