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. 2014 May 6;16(3):229–234.e1. doi: 10.1016/j.neo.2014.03.003

Table 3.

Risk of Hematological Malignancies among Individuals with AUDs by Age at Identification.

Disease
< 40
40-60
60 +
O SIR 95% CI O SIR 95% CI O SIR 95% CI
Non-Hodgkin lymphoma 150 0.97 0.82 1.13 420 0.72 0.65 0.79 371 0.53 0.47 0.58
 Diffuse large B cell 28 1.34 0.89 1.94 68 0.96 0.75 1.22 35 0.57 0.40 0.79
 Follicular 9 0.93 0.42 1.77 34 0.77 0.53 1.08 19 0.59 0.36 0.93
Hodgkin disease 102 0.92 0.75 1.11 97 0.73 0.59 0.89 26 0.36 0.23 0.52
 Mixed cellularity classic 9 1.05 0.48 2.00 7 0.95 0.38 1.97 2 0.49 0.05 1.82
 Nodular sclerosis classic 44 1.10 0.80 1.47 19 1.20 0.72 1.88 7 1.23 0.49 2.56
Myeloma 15 0.98 0.55 1.62 104 0.77 0.63 0.94 77 0.34 0.27 0.43
Leukemia 120 0.61 0.50 0.72 160 0.55 0.47 0.65 113 0.40 0.33 0.48
 Acute lymphatic leukemia 59 0.62 0.47 0.80 12 0.37 0.19 0.64 1 0.06 0.00 0.37
 Acute myeloid leukemia 20 0.57 0.35 0.88 25 0.29 0.19 0.43 18 0.19 0.11 0.30
 Chronic myeloid leukemia 19 0.80 0.48 1.25 26 0.49 0.32 0.72 18 0.45 0.26 0.71
All 387 0.81 0.73 0.89 781 0.68 0.64 0.73 587 0.46 0.42 0.49

O, observed number of cases; SIR, standardized incidence ratio; CI, confidence interval.

Bold type, 95% CI does not include 1.00.