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. 2014 Apr 13;16(3):265–278.e13. doi: 10.1016/j.neo.2014.03.001

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Copyright © 2014 Neoplasia Press, Inc. All rights reserved.

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(A) The promotive effect of rCTHRC1 protein was blocked by Wnt5a neutralizing antibody but not blocked by Wnt3a neutralizing antibody shown from cell migration assay in vitro. (B) Quantification analysis of migrated cells were performed for six randomly selected fields (original magnification:200 ×). (C) The promotive effect of rCTHRC1 protein was partially blocked by Rac1 inhibitor (NSC23766) as well as ROCK inhibitor (Y-27632) shown from cell migration assay. (D) Quantification analysis of migrated cells were performed for six randomly selected fields (original magnification:200 ×). (*, P < 0.05; **, P < 0.01).