Table 1.

Relationship between CTHRC1 expression and clinicopathologic features of GIST patients(^*, P < 0.05; **, P < 0.01).

Variable		CTHRC1(n = 412)
		Low	High	P
Age$	≤ 59 years	31	49	0.458
	> 59 years	114	218
Gender	Male	65	158	0.005
	Female	80	109
Tumor site	Stomach	100	128	< 0.001
	Small bowel	28	93
	Colon	12	9
	Other sites	5	37
Tumor size(cm)	≤ 2	30	7	< 0.001
	> 2&≤5	102	61
	> 5&≤10	9	127
	> 10	4	72
Mitoses per 50 HPFs	≤ 5	138	170	< 0.001
	> 5&≤10	2	52
	> 10	5	45
Modified NIH criteria	Very low risk	30	2	< 0.001
	Low risk	101	51
	Intermediate risk	4	58
	High risk	10	156
NIH invasion	1	30	2	< 0.001
	2	101	51
	3	4	58
	4	5	101
	5	5	55
Tumor bleeding	No	131	220	0.030
	Yes	14	47

Abbreviations: HPF, high power field of the microscope; NIH, National Institutes of Health.

The P value in bold emphasize statistical significance (P<0.001).

^$Median age of total 412 patients was 59 years.