Table 1B. Spectral domain optical coherence tomography analysis of pigment epithelial detachment after switching to aflibercept in eyes with refractory neovascular age-related macular degeneration (n=15).
| Parameter | Baseline mean±SD (range) | 6 Months mean±SD (range) | 12 Months mean±SD (range) | P-valuea |
|---|---|---|---|---|
| BCVA (logMAR) | 0.37±0.26 (0.1–0.90) | 0.37±0.23 (0–0.83) | 0.37±0.26 (0–1) | 0.85 |
| PED Maximal Height (μm) | 288.73±175.91 (110–635) | 240.60±135.81 (68–510) | 248.27±146.22 (90–506) | 0.0019 |
| PED greatest basal diameter (μm) | 2350.93±1067.58 (457–4392) | 2075±1097.06 (489–4470) | 1896.33±782.25 (447–3528) | 0.029 |
Abbreviations: BCVA, best-corrected visual acuity; logMAR, logarithm of minimal angle of resolution; PED, pigment epithelial detachment.
Maximal height is the distance between the outer border of Bruch's membrane and inner border of RPE.
a
Paired t-test, baseline compared with 12 months follow-up.