Figure 5.

Influence of integrin α5 knockdown on tumor cell adhesion and motility. KTC^par and KTC^res cells were transfected with α5 siRNA or scrambled siRNA, and knockdown was controlled by Western blot analysis (A). Cells were then subjected to the HUVEC, collagen, and fibronectin adhesion assay (B) or to the chemotaxis assay (C). Values are shown as percentage difference to controls, set to 100%. Each diagram represents one of six experiments. * indicates significant difference to the siRNA-free control.