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Sox2 is coexpressed with GFAP, nestin, and vimentin in neurosphere-derived GBM xenografts. (A) Coexpression of Sox2 (red) with the IF proteins (green) nestin, GFAP, and vimentin in HF2303 and HF2596 GBM mouse xenografts. Nuclei counterstained with DAPI. Scale, 40 μm. (B) Sox2 and nestin are expressed in xenografts formed from HF2303 neurospheres or low-passage 10% FBS cultures (P4) and downregulated in higher passage (P20) 10% FBS serum cultures. Scale, 20 μm.
