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. 2014 May 24;16(4):354–364.e3. doi: 10.1016/j.neo.2014.04.005

Figure 5.

Figure 5

Elevated MMP expression in resistant cells. Quantitation of MMP expression in sensitive and resistant cells grown in physiological or acidic pH media for 24 hours. Transcripts were normalized to β-actin expression before analysis. (A) Ratio of expression of MMP-2, -3, -9 and -13 in LL/2R and PC3MS cultured in acidic media relative to cells cultured in physiological media. (B) Ratio of expression of MMP-2, -3, -9, and -13 in LL/2R cells relative to expression in PC3MS cells cultured in acidic and physiological media. Data are the average of three independent experiments and is reported as mean ± SD. *P < .05. R, resistant; S, sensitive.