Figure 4.

Scanning electron microscope (SEM) images of biofilms grown with and without sinefungin. Panels (a), (b), and (c) are representative of SEM images of biofilms without sinefungin; the biofilm is thick and well organized with a three-dimensional structure. Panels (d), (e), and (f) are representative of SEM images of biofilm grown with 35 μg mL⁻¹ sinefungin; biofilms are thin and scattered; and clumps of cells are seen with no organized structure. The scale bars of the figure are 10, 5, and 3 μm.