Table 3.
Hematological findings of normal and different types of thalassemia and Hb E.
| Group (n) | Hb (g/L) | MCV (fL) | MCH (pg) | Hb A2/E (%) |
|---|---|---|---|---|
| I. Normal and heterozygous α-thalassemia 2 (n = 101) | 141 ± 13.4 | 84.9 ± 4.31 | 30.0 ± 1.68 | — |
| II. Homozygous α-thalassemia 2 and heterozygous α-thalassemia 1 (n = 4) | 129 ± 10.5 | 65.1 ± 2.44 | 21.4 ± 0.90 | 2.9 ± 0.25 |
| III. Heterozygous β-thalassemia without α-thalassemia (n = 1) | 139 | 62.2 | 20.0 | 5.0 |
| IV. Heterozygous Hb E without α-thalassemia (n = 6) | 134 ± 9.6 | 75.1 ± 3.39 | 25.2 ± 1.16 | 26.2 ± 0.58 |
| V. Double heterozygotes for Hb E/α-thalassemia 1 (n = 2) | 123 ± 6.4 | 67.5 ± 1.84 | 21.8 ± 0.57 | 19.3 ± 0.64 |
| VI. Homozygous Hb E without α-thalassemia (n = 1) | 127 | 61.6 | 19.7 | 74.5 |
| VII. Homozygous Hb E with heterozygous α-thalassemia 2 (n = 1) | 139 | 67.6 | 22.0 | 75.4 |
| P value∗ | 0.05 | <0.001 | <0.001 | <0.001 |
Hematological data are expressed either as mean ± standard deviation (SD) or raw data where appropriate (n = 1, groups III, VI, and VII).
Hb: hemoglobin; g/L: gram per liter; MCV: mean corpuscular volume; fL: femtoliter; MCH: mean corpuscular hemoglobin; pg: picogram.
*P value was calculated by using the nonparametric Kruskal-Wallis test (groups I, II, IV, and V were compared).