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editorial
. 2014 Jul 14;5:245. doi: 10.3389/fphys.2014.00245

Figure 2.

Figure 2

There is no unit and all figures are representing increase and decrease in parameters, curves, and arrows are representing hypothetical relationship between parameters. *Both high levels of ROS and antioxidants are carcinogen; however it seems that in certain conditions such as tuberculosis and smoking slightly increased ROS production could be beneficial rather than hazardous. Optimal equilibrium point is shifted in these conditions to the right. Increased risk of cancer due to other oncogenes (i.e., smoking) needs more alert immune system and more oxidative stress, hence optimal protection point will shift to the right.