Table 2.
Comparison of the clinical and pathologic parameters between patients with and without elevated urinary KIM-1/Cr
| Variable | Without elevated urinary KIM-1/Cr (n = 33) | With elevated urinary KIM-1/Cr (n = 18) | P value |
|---|---|---|---|
| Male/female (n) |
11/22 |
8/10 |
0.547 |
| Age (years) |
30.03 ± 7.96 |
27.33 ± 7.89 |
0.252 |
| Time from onset (months) |
5(0.5, 60) |
3(0.33, 84) |
0.501 |
| With/without prior infection |
13/20 |
10/8 |
0.378 |
| With/without gross hematuria |
16/17 |
9/9 |
1.000 |
| Systolic blood pressure (mmHg) |
118.18 ± 10.95 |
115.28 ± 13.98 |
0.416 |
| Diastolic blood pressure (mmHg) |
74.24 ± 8.11 |
71.11 ± 10.51 |
0.241 |
| Proteinuria (g/24 h) |
0.52 ± 0.20 |
0.62 ± 0.24 |
0.149 |
| Serum creatinine (μmol/L) |
74.24 ± 13.09 |
75.69 ± 13.10 |
0.707 |
| eGFR(ml/min/1.73 m2) |
105.24 ± 23.19 |
104.56 ± 16.27 |
0.912 |
| Serum IgA (mg/dL) |
318.05 ± 111.82 |
374.27 ± 127.36 |
0.180 |
| Serum Complement 3 (mg/dL) |
93.73 ± 23.15 |
96.38 ± 19.04 |
0.774 |
| Mesangial hypercellularity (M0/M1) |
29/4 |
13/5 |
0.249 |
| Segmental glomerulosclerosis (S0/S1) |
28/5 |
17/1 |
0.405 |
| Endocapillary hypercellularity (E0/E1) |
29/4 |
15/3 |
0.686 |
| Tubular atrophy/interstitial fibrosis (T0/T1/T2) |
33/0/0 |
13/5/0 |
0.004* |
| With/without extracapillary proliferation (cresecents) |
6/27 |
9/9 |
0.026* |
| With/without global glomerulosclerosis |
13/20 |
10/8 |
0.378 |
| With/without vascular lesions | 6/27 | 8/10 | 0.057 |
*Being statistically significant. Since there was no patient with T2 in two groups, distribution of the variable of tubular atrophy/interstitial fibrosis was compared by chi-square test.