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. 2014 Jul 3;10(1):34. doi: 10.1186/1710-1492-10-34

Table 4.

Sensitivity analysis with multivariable models * to evaluate the association of TZDs with asthma exacerbations and steroid prescriptions among patients who were most adherent to oral diabetes therapy (ReComp scores ≥ 0.8)

Event Risk of any event
Risk of multiple events
OR 95%CI IRR 95%CI
Asthma Exacerbation
0.64
0.47 – 0.85
0.65
0.48 – 0.88
Steroid prescription 0.68 0.57 – 0.81 0.65 0.54 – 0.79

*Adjusted for age, gender, race, free care, distance to VA facility, number of primary care encounters, Diagnostic Cost Group score, Diabetes Severity Index score, prior year exacerbations, atrial fibrillation, heart failure, ischemic heart disease, alcohol or drug abuse, and depression, respiratory medications.

Logistic regression with outcome being presence of asthma exacerbation or steroid prescription. Results are presented in odds ratios (OR) and 95% confidence intervals (CI).

Negative binomial regression with outcome being number of asthma exacerbations or number of steroid prescriptions. Results are presented in incidence rate ratios (IRR) and 95% confidence intervals.