Table 1.
Subject demographics at baseline.
| N | Gender M/F | Age | Years of education | APOE e4 carriers | |
|---|---|---|---|---|---|
| WHOLE AddNeuroMed DATASETa | |||||
| AD | 119 | 41/78 | 75.5 ± 6.0 | 8.0 ± 4.0 | 64 [54%] |
| CTL | 110 | 50/60 | 73.0 ± 6.5 | 10.8 ± 4.8 | 31 [28%] |
| MCI | 119 | ||||
| MCI-c | 22 | 14/8 | 72.8 ± 6.4 | 9.2 ± 4.3 | 13 [59%] |
| MCI-nc | 97 | 46/51 | 74.7 ± 5.4 | 8.8 ± 4.3 | 26 [27%] |
| AddNeuroMed LONGITUDINAL DATASETb | |||||
| AD | 62 | 16/46 | 74.0 ± 5.6 | 8.6 ± 4.0 | 34 [55%] |
| CTL | 79 | 35/44 | 74.5 ± 5.5 | 10.3 ± 4.5 | 25 [32%] |
| MCI | 73 | ||||
| MCI-c | 13 | 8/5 | 71.8 ± 5.7 | 9.5 ± 4.3 | 8 [62%] |
| MCI-nc | 60 | 30/30 | 75.7 ± 0.7 | 9.2 ± 4.4 | 15 [25%] |
Data is presented as mean ± standard deviation. The longitudinal dataset consists of individuals followed longitudinally over 1-year and assessed using cognitive batteries and MRI scans. AD, Alzheimer disease; CTL, healthy control; MCI-c, MCI converters; MCI-nc, MCI non-converters; MCI, Mild cognitive impairment.
a
Significant differences in Age (AD vs. CTL Mann-Whitney test P = 0.002) and years of education (AD vs. CTL and MCI vs. CTL Mann-Whitney test P < 0.004).
b
Significant differences in Age (MCI-c vs. MCI-nc Mann-Whitney test P = 0.04), gender (AD vs. MCI Mann-Whitney test P = 0.009) and years of education (AD vs. CTL Mann-Whitney test P = 0.014).