Table 1.
Fusion partners of EWSR1-rearrangements in different soft tissue tumors. Overlapping rearrangements in different histopathological entities are in bold. Adapted from [44,45].
| Histological type | Translocation | EWS-rearrangements |
|---|---|---|
| Ewing’s Sarcoma | t(11;22)(q24;q12) | EWSR1-FLI1 |
| t(21;22)(q22;q12) | EWSR1-ERG | |
| t(7;22)(q22;q12) | EWSR1-ETV1 | |
| t(17;22)(q21;q12) | EWSR1-ETV4 | |
| t(2;22)(q36;q12) | EWSR1-FEV | |
| inv(22)(q12q12) | EWSR1-PATZ1 | |
| t(2;22)(q31;q12) | EWSR1-SP3 | |
| t(20;22)(q13;q12) | EWSR1-NFATC2 | |
| t(4;22)(q31;12) | EWSR1-SMARCA5 | |
| t(17;22)(q12;q12) | EWSR1-E1AF | |
| inv(22)(q21;12) | EWSR1-ZSG | |
| Angiomatoid fibrous histiocytoma | t(12;22)(q13;q12) | EWSR1-ATF1 |
| t(2;22)(q33;q12) | EWSR1-CREB1 | |
| Clear cell sarcoma | t(12;22)(q13;q12) | EWSR1-ATF1 |
| t(2;22)(q33;q12) | EWSR1-CREB1 | |
| Malignant gastrointestinal neuroectodermal tumor | t(12;22)(q13;q12) | EWSR1-ATF1 |
| t(2;22)(q33;q12) | EWSR1-CREB1 | |
| Myoepithelial tumor of soft tissue and bone | t(1;22)(q23;q12) | EWSR1-PBX1 |
| t(19;22)(q13;q12) | EWSR1-ZNF444 | |
| t(6;22)(p21;q12) | EWSR1-POU5F1 | |
| Extraskeletal myxoid chondrosarcoma | t(9;22)(q22;q12) | EWSR1-NR4A3 |
| Myxoid liposarcoma | t(12;22)(q13;q12) | EWSR1-DD1T3 |