Table 3.
Serum levels of liver fibrosis mediators
| Everolimus patients (n = 30) | CNI patients (n = 30) | P value | |
| VCAM (ng/mL) | 68.25 (25.98-135.17) | 58.88 (35.30-115.52) | 0.668 |
| PIIINP (ng/mL) | 172.4 (119.75-1195.90) | 879.40 (140.10-1555.15) | 0.193 |
| IP-10 (pg/mL) | 86.01 (51.10-210.91) | 79.61 (59.2-172.64) | 0.669 |
| HGF (pg/mL) | 225.17 (163.30-320.17) | 205.53 (152.59-297.86) | 0.363 |
| Angiopoietin (ng/mL) | 26.97 (19.58-32.25) | 30.108 (24.60-38.8) | 0.122 |
| TNF-α (ng/mL) | 41.12 (38.35-44.8) | 42.70 (40.20-45.07) | 0.435 |
| IL-10 (pg/mL) | 8.52 (6.07-9.23) | 8.66 (6.95-9.40) | 0.856 |
| TGF-β (ng/mL) | 12.7 (3.7-133.6) | 152.5 (14.4-333.2) | 0.009 |
| HA (ng/mL) | 702.89 (329.4-838.2) | 1513.6 (691.9-1951.4) | 0.001 |
| PDGF (ng/mL) | 1.5630 (1.4663-1.6369) | 1.5630 (1.4616-1.6369) | 0.720 |
Variables are expressed as medians and interquartillic range. VCAM: Vascular cell adhesion molecule; PIIINP: Amino-terminal propeptide of type III procollagen; IP10: Interferon-inducible protein 10 calcineurin inhibitor; TNF-α: Transforming necrosis factor alpha; TGF: Tissue growth factor; HGF: Hepatocyte growth factor; HA: Hyaluronic acid; PDGF: Platelet derived growth factor.