Table 4.
Stratified analysis according to factors that could influence liver fibrosis
| TGF-β (ng/mL) | P value | HA (ng/mL) | P value | |
| All patients | ||||
| E (n = 30) | 12.7 (3.7-133.6) | 0.009 | 702.89 (329.4-838.2) | 0.001 |
| CNI (n = 30) | 152.5 (14.4-333.2) | 1513.6 (691.9-1951.4) | ||
| Free of neoplasia | ||||
| E (n = 29) | 11.1 (3.2-22.4) | 0.005 | 754.8 (351.3-837) | 0.030 |
| CNI (n = 22) | 137.5 (14.4-333.2) | 1296.7 (703.7-1936.1) | ||
| Time from LT > 5 yr | ||||
| E (n = 17) | 16.5 (7.6-264.6) | 0.010 | 462.0 (351.3-770.3) | 0.002 |
| CNI (n = 16) | 296.8 (125.4-337.1) | 1084.7 (523.7-1665.8) | ||
| Donor age > 50 yr | ||||
| E (n = 12) | 14.0 (6.0-67.1) | 0.06 | 910.0 (589.2-1510.8) | 0.005 |
| CNI (n = 15) | 96.0 (14.5-297.1) | 1897.0 (1519-2136.5) | ||
| Biliary complications | ||||
| E (n = 12) | 20.6 (7.6-265) | 0.110 | 516.75 (235.6-1079.4) | 0.010 |
| CNI (n = 10) | 272.3 (16.5-403.4) | 1545.37 (1085.8-1888.7) | ||
| Recurrent HCV | ||||
| E (n = 10) | 6.5 (1.6-15.3) | 0.260 | 914.55 (768.8-1513.6) | 0.410 |
| CNI (n = 11) | 14.5 ( 6.1-225) | 1991.17 (1532.4-2168.9) | ||
Variables are expressed as medians and interquartillic range. TGF-β: Transforming growth factor-β; HA: Hyaluronic acid; E: Everolimus; CNI: Calcineurin inhibitors.