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. 2014 Jun 24;4(2):133–140. doi: 10.5500/wjt.v4.i2.133

Table 4.

Stratified analysis according to factors that could influence liver fibrosis

TGF-β (ng/mL) P value HA (ng/mL) P value
All patients
E (n = 30) 12.7 (3.7-133.6) 0.009 702.89 (329.4-838.2) 0.001
CNI (n = 30) 152.5 (14.4-333.2) 1513.6 (691.9-1951.4)
Free of neoplasia
E (n = 29) 11.1 (3.2-22.4) 0.005 754.8 (351.3-837) 0.030
CNI (n = 22) 137.5 (14.4-333.2) 1296.7 (703.7-1936.1)
Time from LT > 5 yr
E (n = 17) 16.5 (7.6-264.6) 0.010 462.0 (351.3-770.3) 0.002
CNI (n = 16) 296.8 (125.4-337.1) 1084.7 (523.7-1665.8)
Donor age > 50 yr
E (n = 12) 14.0 (6.0-67.1) 0.06 910.0 (589.2-1510.8) 0.005
CNI (n = 15) 96.0 (14.5-297.1) 1897.0 (1519-2136.5)
Biliary complications
E (n = 12) 20.6 (7.6-265) 0.110 516.75 (235.6-1079.4) 0.010
CNI (n = 10) 272.3 (16.5-403.4) 1545.37 (1085.8-1888.7)
Recurrent HCV
E (n = 10) 6.5 (1.6-15.3) 0.260 914.55 (768.8-1513.6) 0.410
CNI (n = 11) 14.5 ( 6.1-225) 1991.17 (1532.4-2168.9)

Variables are expressed as medians and interquartillic range. TGF-β: Transforming growth factor-β; HA: Hyaluronic acid; E: Everolimus; CNI: Calcineurin inhibitors.