Table 4.

Expression cut-offs from the Kaplan-Meier and from the rules.

Probe set IDa	NB-hypo-IIb	Overallc				Relapse freed
		Expression cut-offe		Worsef		Expression cut-offe		Worsef
		Kaplan-Meier	Rulex	Kaplan-Meier	Rulex	Kaplan-Meier	Rulex	Kaplan-Meier	Rulex
1	223172_s_at	107	73	high	high	107	73	high	high
2	200738_s_at	1553	1846	high	high	1553	1846	high	high
3	209446_s_at	69	57	high	high	69	57	high	high
4	226452_at	280	326	high	high	280	326	high	high
5	217356_s_at	706	721	high	high	706	721	high	high
6	236180_at	18	13	hgih	hgih	13	13	high	hgih
7	202022_at	101	131	low	low	138	131	low	low
8	224314_s_at	25	29	high	high	25	29	high	high
9	206686_at	36	26	high	high	36	26	high	high
10	223193_x_at	495	324	high	high	572	324	high	high
11	230630_at	19	23	low	low	35	23	low	low

^a Probe sets ID indicates the numerical identified of the probeset.

^b NB-hyp-II indicates the list of probe sets of the NB-hypo signature belonging to the rules.

^c Overall indicates the survival time between the time of an event or last follow up and the time of diagnosis.

^d Relapse free indicates the survival time between the first relapse and the time of diagnosis.

^e Expression cut-off indicates the optimal cut-off point of each probe set resulting from the Kaplan-Meier scan and from the rules.

^f Worse indicates whether high or low expression of a given probe set is associated to the worse survival. Worse survival are calculated from the Kaplan-Meier curve or from the conditions included into the rules.