Table 2.
Age | Loading dose (administer within 3 hours) | Subsequent dose |
---|---|---|
≥12 years::adult protocol |
1 g intravenously over 10 minutes |
1 g intravenous infusion over 8 hours |
<12 years | 15 mg/kg intravenously over 10 minutes (maximum dose 1 g) | 2 mg/kg/hr intravenous infusion over 8 hours or until bleeding stops |
The Hospital for Sick Children Massive Hemorrhage Protocol for the use of tranexamic acid in pediatric trauma. April 2014. Adapted from Royal College of Paediatrics and Child Health: Evidence statement - Major trauma and the use of tranexamic acid in children [39].