Rates of [U-14C]-d-glucose uptake in adipocytes under basal, physiologic (50 pmol insulin/L), and supraphysiologic (20 nmol insulin/L) conditions, measured at baseline and after 6-wk ingestion of ≥700 kcal before 1100 daily (breakfast group; n = 13) or abstinence from all energy-providing nutrients until at least 1200 daily (fasting group; n = 16). Values are means ± SEs. Three-factor ANOVA (treatment × time × insulin) showed a significant effect of treatment (F = 4.2, P = 0.05) and insulin (F = 17.3, P < 0.001) with no significant effect of time nor any interaction of these factors. Ins, insulin.