Table 1.

List of the 19 systemic lupus erythematosus loci included in this study and their association with systemic lupus erythematosus in our samples ^a

SNP	Gene locus b	Chromosome	Position	SLE c	Control c	OR (95% CI)	P-value
rs2476601	PTPN22	1	114377568	0.099	0.074	1.37 (1.15 to 1.63)	4.3 × 10−4
rs1801274	FCGR2A	1	161479745	0.509	0.475	1.15 (1.04 to 1.27)	6.2 × 10−3
rs2205960	TNFSF4	1	173191475	0.264	0.217	1.29 (1.15 to 1.45)	1.0 × 10−5
rs7574865	STAT4	2	191964633	0.323	0.233	1.57 (1.41 to 1.76)	1.2 × 10−15
rs6445975	PXK	3	58370177	0.268	0.231	1.22 (1.09 to 1.37)	6.2 × 10−4
rs17266594	BANK1d	4	98488450	0.749	0.711	1.21 (1.09 to 1.36)	6.6 × 10−4
rs3131379	MSH5	6	31721033	0.145	0.072	2.18 (1.85 to 2.58)	4.2 × 10−21
rs729302	IRF5	7	122930164	0.744	0.690	1.31 (1.17 to 1.46)	2.5 × 10−6
rs10488631	IRF5d	7	128594183	0.183	0.101	1.99 (1.72 to 2.31)	1.8 × 10−20
rs10954213	IRF5	7	128589427	0.680	0.641	1.19 (1.07 to 1.32)	1.1 × 10−3
rs13277113	C8orf13-BLK	8	11349186	0.308	0.247	1.35 (1.21 to 1.51)	8.1 × 10−8
rs4963128	KIAA1542	11	589564	0.698	0.656	1.21 (1.09 to 1.34)	5.0 × 10−4
rs1143679	ITGAM	16	31276811	0.236	0.158	1.65 (1.45 to 1.87)	7.0 × 10−15
rs2304256	TYK2	19	10475652	0.766	0.725	1.24 (1.11 to 1.39)	2.0 × 10−4
rs5754217	UBE2L3	22	21939675	0.253	0.216	1.24 (1.10 to 1.39)	3.6 × 10−4
rs2230926	TNFAIP3	6	138196066	0.074	0.040	1.89 (1.52 to 2.35)	8.5 × 10−9
rs573775	ATG5	6	106764866	0.297	0.267	1.16 (1.04 to 1.29)	8.8 × 10−3
rs2187668	HLA-DQA1	6	32605884	0.200	0.106	2.11 (1.83 to 2.43)	1.2 × 10−25
rs10798269	1q25.1	1	173309713	0.729	0.685	1.24 (1.11 to 1.38)	1.3 × 10−4

^aSLE, Systemic lupus erythematosus; SNP, Single-nucleotide polymorphism. ^bThe 13 first loci are shared with those studied by Hughes et al. [1]. ^cRisk allele frequencies in patients with SLE (n = 1,457) and healthy controls (n = 1,728). ^dr² = 0.94 with rs10516487 used for BANK1 by Hughes et al. [9] and r² = 0.94 for rs2070197 used for IRF5 by Hughes et al. [9].