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Patient distribution according to molecular characteristics and St Gallen 2011 and 2013 intrinsic molecular subtype definitions. The threshold of ≥14% for Ki-67 in the 2011 definition was derived from comparison with gene array data as a prognostic factor [3,4], whereas the threshold of ≥20% in the 2013 definition was approved by the majority of the expert consensus panel [1]. HER2, Human epidermal growth factor receptor 2; PgR, Progesterone receptor.
