Table 2.
CV medication ( n = 13,847) | Without CV medication ( n = 5,896) | P value | |
---|---|---|---|
Age |
|
|
|
Mean |
79.6 ± 7.2 |
77.4 ± 8.9 |
<0.001 |
Range |
33 to 103 |
27 to 97 |
|
Gender |
|
|
|
Female (%) |
55.9 |
64.4 |
<0.001 |
Male (%) |
44.1 |
35.6 |
|
MMSE |
|
|
|
Mean |
21.4 ± 4.9 |
21.3 ± 5.2 |
<0.001 |
Range |
0 to 30 |
0 to 30 |
|
Living alone (%) |
43.7 |
45.7 |
0.006 |
ChEIs (%) |
46.1 |
58.5 |
<0.001 |
NMDA antagonists (%) |
10.6 |
10.3 |
0.028 |
Number of drugs |
|
|
|
Mean |
5.8 ± 3 |
3,0 ± 2.5 |
<0.001 |
Range |
0 to 24 |
0 to 21 |
|
AD (%) |
34.9 |
56.0 |
<0.001 |
MixD (%) |
28.9 |
20.4 |
<0.001 |
VaD (%) |
30.3 |
13.2 |
<0.001 |
DLB (%) |
2.6 |
4.2 |
<0.001 |
FTD (%) |
1.6 |
3.2 |
<0.001 |
PDD (%) | 1.7 | 2.9 | <0.001 |
AD, Alzheimer’s disease; ChEI, cholinesterase inhibitor; CV, cardiovascular; DLB, dementia with Lewy bodies; FTD, frontotemporal dementia; MixD, mixed dementia; MMSE, Mini Mental State Examination; NMDA, N-methyl-d-aspartate; PDD, Parkinson’s disease dementia; VaD, vascular dementia.