Table 1.
Characteristics of the patients a
| Characteristics | All patients ( N = 163) | Mild or moderately severe AP ( n = 138) | P- value b |
Severe AP (
n
= 25) |
|||
|---|---|---|---|---|---|---|---|
| All ( N = 25) | MMS <2 ( n = 14) | P- value | MMS ≥2 ( n = 11) | ||||
| Men |
120 (73.6) |
96 (69.6) |
0.006 |
24 (96.0) |
13 (92.9) |
NS |
11 (100.0) |
| Age, years |
48 (18 to 87) |
49 (18 to 87) |
NS |
43 (29 to 81) |
41 (29 to 81) |
NS |
51 (29 to 69) |
| Etiology |
|
|
|
|
|
|
|
| Alcohol |
113 (69.3) |
91 (65.9) |
0.028 |
22 (88.0) |
11 (78.6) |
NS |
11 (100) |
| Biliary |
35 (21.5) |
34 (24.6) |
0.021 |
1 (4.0) |
1 (7.1) |
NS |
0 |
| Other cause |
11 (6.7) |
9 (6.5) |
NS |
2 (8.0) |
2 (14.3) |
NS |
0 |
| Idiopathic |
4 (2.5) |
4 (2.9) |
NS |
0 |
0 |
NS |
0 |
| Onset of symptoms, hr |
24 (1 to 72) |
24 (1 to 72) |
NS |
24 (3 to 72) |
18 (3 to 48) |
<0.001 |
48 (24 to 72) |
| C-reactive protein, mg/L |
19 (3 to 435) |
16 (3 to 426) |
0.002 |
94 (3 to 435) |
30 (3 to 229) |
<0.001 |
294 (22 to 435) |
| Creatinine, μmol/L |
64 (31 to 1086) |
62 (31 to 313) |
<0.001 |
92 (47 to 1086) |
68 (47 to 147) |
<0.001 |
248 (92 to 1086) |
| Calcium, mmol/L |
2.2 (1.27 to 2.73) |
2.23 (1.27 to 2.73) |
<0.001 |
1.86 (1.39 to 2.30) |
2.04 (1.49 to 2.30) |
0.013 |
1.67 (1.39 to 2.17) |
| Length of hospital stay, days |
6 (1 to 93) |
5 (1 to 41) |
<0.001 |
26 (1 to 93) |
28 (1 to 93) |
NS |
17 (1 to 49) |
| Mechanical ventilation |
25 (15.3) |
2 (1.4) |
<0.001 |
23 (92.0) |
13 (92.9) |
NS |
10 (90.9) |
| Renal replacement therapy |
16 (9.8) |
0 |
<0.001 |
16 (64.0) |
7 (50.0) |
NS |
9 (81.8) |
| OD within 24 hours |
30 (18.4) |
10 (7.2) |
<0.001 |
20 (80.0) |
9 (64.3) |
NS |
11 (100) |
| OD on days 1 to 7 |
5 (3.1) |
0 |
<0.001 |
5 (20.0) |
5 (37.5) |
NS |
0 (0) |
| Mortality | 8 (4.9) | 1 (0.7) | 0.014 | 7 (28.0) | 2 (14.3) | NS | 5 (45.5) |
aAP, Acute pancreatitis; MMS, Modified Marshall score; NS, Not significant; OD, organ dysfunction. bSignificance of the difference between mild or moderately severe AP (n = 138) and severe AP (n = 25). The severe AP group is categorized into two subgroups: admission modified Marshall Score <2 or ≥2. Data are median (range) or n (%).