Fig. 5. Compartment specific expression patterns of the Dlx6 gene at E9.5.

The position of the Dlx6 gene is shaded, with exons shown at the bottom of the figure in darker blue and introns in light blue. The E9.5 cranial mesenchyme (top) shows very low expression, with few RNA-seq reads (small rectangles). The olfactory placode, bottom, shows strong Dlx6 expression, with normal splicing. The lines show RNA-seq reads that spanned introns. In addition there are multiple RNA-seq reads from the 5′ flanking region of the gene (to the left), that did not showing splicing (no lines). The maxillary arch showed strong expression of Dlx6, as well as strong expression of a spliced antisense noncoding transcript in the 5′ promoter region, indicated by the lines marking the opposite strand (5′ OS) intron. In the mandibular arch there is strong expression of the Dlx6 gene, the 5′ antisense spliced transcript, and also an antisense transcript that initiates 3′ of the Dlx6 gene (3′ OS), with both antisense transcripts splicing to exons further 5′ and not shown in this figure.