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. Author manuscript; available in PMC: 2014 Nov 14.
Published in final edited form as: Sci Transl Med. 2014 May 14;6(236):236ra63. doi: 10.1126/scitranslmed.3008104

Figure 5. PGT128 family antibodies can utilize alternate glycan sites in the high-mannose patch to neutralize isolates when the N332 or N334 glycan sites are removed by alanine mutagenesis.

Figure 5

Neutralization potency of the PGT128 antibody family was measured on a panel of (A) 92RW020, (B) 92TH021 and (C) JR-CSF glycan mutant viruses for which N-linked glycan sites in the V3 region were removed alone or in combination with other N-linked glycan sites.

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