a Representative in vivo 1H MR spectra acquired from the hippocampus of Glud1 transgenic (Tg, top) and wild type (wt, bottom) mice. b Representative in vivo 1H MR spectra acquired from the striatum of Tg (top) and wt (bottom) mice. Neurochemical abbreviations are alanine (Ala), aspartate (Asp), ascorbate (Asc), choline (Cho), creatine (Cr), γ-aminobutyric acid (GABA), glucose (Glc), glutamate (Glu), glutamine (Gln), glutathione (GSH), glyceropho-sphoryl-choline (GPC), phosphorylcholine (PCho), myo-Inositol (mI), lactate (Lac), N-acetylaspartate (NAA), N-acetylaspartylglutamate (NAAG), phosphocreatine (PCr), phosphorylethanolamine (PE), and serine (Ser)