Dendrogram showing members of the TMC gene family from several model organisms. Nematode (Ce), fruitfly (Dm), zebrafish (Dr), xenopus (Xt), mouse (Mm) and human (Hs) TMCs are shown. TMC1–3 form one group, TMC5–6 form a second and a third includes TMC4, 7 and 8. Human TMCs are shown in blue and mouse TMCs are shown in red. The dendrogram was generated using Clustal Omega for multiple sequence alignments, Protdist from PHYLIP to calculate distances and FigTree to draw the tree.