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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Pflugers Arch. 2014 Feb 11;466(8):1501–1516. doi: 10.1007/s00424-014-1448-8

Figure 1.

Figure 1

SLC4 HCO32-(CO3−) transporters whose function is defined: A) AE1-3: Na+-independent Cl−-HCO3− exchangers; B) NBCn1 and NBCn2: electroneutral Na+-HCO3− transporters. It should be noted that under certain experimental conditions, NBCn2 can also mediate Na+-dependent Cl−-HCO3− exchange; C) NBCe1 and NBCe2: electrogenic Na+-CO32-(HCO3−) transporters with either a 1:2 or 1:3 stoichiometry; D) NDCBE: Na+-driven Cl−-CO3− exchanger. Not depicted is AE4 whose function is not clearly characterized. The SLC4A11 gene product does not transport HCO32−(CO3−) nor is its function clearly defined.