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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: Pflugers Arch. 2014 Feb 11;466(8):1501–1516. doi: 10.1007/s00424-014-1448-8

Figure 4.

Figure 4

Transport models of various cell types expressing NBCe1-A. A) Proximal tubule cell; B) Corneal epithelial cell; C) Maturation stage ameloblast; D) Pancreatic duct cell. Note that in patients with NBCe1 a mutation, a pancreatic ductal phenotype has not been reported suggesting that pancreatic ductal cells likely have compensatory mechanisms mediating basolateral bicarbonate uptake. Patients typically have an increased blood lipase and amylase suggesting abnormal acinar involvement however unlike the rat, the human pancreatic acinus apparently does not express NBCe1-B [106].