Table 3.

fMRI Results for Decision Phase: Group by Decision (Early, Late) Interaction

Voxels	Vol	x	y	z	L/R	Regions within cluster	BA	Early (E)	Late (L)	Abstinent	Relapsed
Early trials: abstinent > relapsed
68	4352	−36	16	14	L	Anterior insula Middle frontal gyrus	9/13	d=1.02	NS	NS	L > E
42	2688	27	2	44	R	Middle frontal gyrus Superior frontal gyrus	6/8	d=0.68	NS	E > L	NS
26	1664	−50	−47	−4	L	Middle temporal gyrus	37	d=1.16	NS	E > L	NS
13	832	36	−48	24	R	Supramarginal gyrus	39	d=1.01	NS	E > L	NS
24	1536	46	2	0	R	Anterior insula	13	d=0.56	NS	NS	NS
15	960	39	24	27	R	Middle frontal gyrus	9	d=0.57	NS	NS	NS
12	768	−41	−4	−11	L	Superior temporal gyrus	21	d=0.61	NS	NS	NS
Late trials: abstinent > relapsed
21	1344	−5	46	−2	L	Anterior cingulate	32	NS	d=1.00	L > E	E > L
Late trials: relapsed > abstinent
13	832	28	4	29	R	Precentral/cingulate gyrus	6	d=0.58	d=0.57	E > L	NS
14	896	18	−20	0	R	Thalamus		NS	d=0.64	E > L	NS

Note: L = left hemisphere. R = right hemisphere. BA = Brodmann Area. Vol = volume in microliters. Talairach coordinates reflect center of mass. All clusters listed were significant at F(1,28) > 4.2 for P<0.05 (0.025 two-tailed) voxelwise corrected for multiple comparisons. d = Cohen’s d effect size between groups.