Table II.
Surgery Type and Medications Administered during Hospitalization, Stratified by the Development of POAF
| Characteristics | POAF N = 10957 (3.0%) |
No POAF N = 359490 (97.0%) |
P value |
|---|---|---|---|
| Type of surgery | <0.001 | ||
| Intracranial | 326 (3.0%) | 8327 (2.3%) | |
| Spinal/Peripheral Nerve | 397 (3.6%) | 31113 (8.7%) | |
| Abdominal | 3895 (35.6%) | 86715 (24.1%) | |
| Genital-urinary | 486 (4.4%) | 26678 (7.4%) | |
| Orthopedic | 2425 (22.1%) | 136725 (38.0%) | |
| Otolaryngologic | 347 (3.2%) | 5279 (1.5%) | |
| Thoracic (Non-cardiac) | 465 (4.2%) | 7582 (2.1%) | |
| Vascular | 570 (5.2%) | 20590 (5.7%) | |
| Miscellaneous | 2046 (18.7%) | 36481 (10.2%) | |
| Peri-Operative Medications | |||
| Statins | 2114 (19.3%) | 77757 (21.6%) | <0.001 |
| Beta-blockers | 3585 (32.7%) | 100575 (28.0%) | <0.001 |
| ACE inhibitors | 2143 (19.6%) | 71323 (19.8%) | 0.466 |
| Angiotensin receptor blockers | 817 (7.5%) | 35416 (9.9%) | <0.001 |
| Anti-arrhythmics | 583 (5.3%) | 4082 (1.1%) | <0.001 |
| Aspirin | 1840 (16.8%) | 48075 (13.4%) | <0.001 |
| Calcium channel blockers | 1140 (10.4%) | 41965 (11.7%) | <0.001 |
| Clopidogrel | 454 (4.1%) | 13114 (3.7%) | 0.007 |
| Prophylactic antibiotics | 9981 (91.1%) | 327752 (91.2%) | 0.774 |
| Pharmacologic VTE prophylaxis | 7103 (64.8%) | 158443 (44.1%) | <0.001 |
| Mechanical VTE prophylaxis | 2232 (20.4%) | 33188 (9.2%) | <0.001 |
| Post-operative therapy received | |||
| IV Amiodarone | 3083 (28.1%) | 1566 (0.4%) | <0.001 |
| IV beta-blocker | 3970 (36.5%) | 14547 (4.1%) | <0.001 |
| IV calcium channel blocker | 2555 (23.3%) | 1335 (0.4%) | <0.001 |
| Digoxin | 5600 (51.1%) | 3192 (0.9%) | <0.001 |
| DC Cardioversion | 810 (7.4%) | 1317 (0.4%) | <0.001 |
Abbreviations: POAF, Post-operative atrial fibrillation; ACE, Angiotensin converting enzyme; VTE, venous thrombo-embolism; IV, intravenous