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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: J Neurosci Res. 2013 Dec 21;92(4):531–541. doi: 10.1002/jnr.23332

Figure 4.

Figure 4

Histological sections of T8 sensory roots (A and B) and dorsal root ganglia (DRG) (C and D) in PWC samples. EM-fixed sensory roots and DRG from control (A,C) and grade 4 (B,D) PWC samples were embedded in resin and stained with PPD and toluidine blue respectively. Compared to controls (A), sensory roots from grade 4 PWC (B) exhibited decreased myelinated axon density. DRG neurons from grade 4 PWC (D) contained numerous cells with condensed cytoplasm (arrowhead) and severely pyknotic nuclei (arrow) that were not present in the DRG neurons from age-matched control dogs (arrowhead and arrow in C denote cytoplasm and nucleus of normal neuron for comparison).