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SOD1 Genotypes. DM is associated with a SOD1:c.118G>A mutation. Homozygosity for the A allele is a risk factor for developing DM in Boxers and PWCs.
| Number of Dogs of Each SOD1 Genotype (age in years) | |||
|---|---|---|---|
| Disease Status - Breed | G/G | A/G | A/A |
| Unaffected PWC | 1 (16) | 4 (13-17) | 2 (13-14) |
| Affected PWC | 0 | 0 | 15 (12-15) |
| Unaffected Boxer | 0 | 4 (8-12) | 2 (9) |
| Affected Boxer | 0 | 0 | 9 (10-12) |
