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. 2014 May 5;16(8):1137–1145. doi: 10.1093/neuonc/nou056

Table 4.

Cox proportional hazards regression analysis for patients aged <15 y at diagnosis comparing SEER vs NRCT (all age-adjusted unless otherwise stated)

Survival Person Years at Risk N Subjects N Deaths Hazard Ratio 95% CI P
All ages
 Pilocytic astrocytoma 10 y 12934 1916 78 0.69 0.44–1.10 .117
 Anaplastic astrocytoma 10 y 559 218 166 0.77 0.57–1.05 .095
 Glioblastoma 10 y 426 263 228 0.72 0.55–0.93 .013
 Medulloblastoma 10 y 5465 1017 369 0.80 0.65–0.99 .036
 PNET 10 y 1355 350 193 0.51 0.38–0.67 <.001
 Ependymoma 10 y 2986 572 204 0.85 0.64–1.12 .240
 Overall 10 y 23725 4336 1238 0.74 0.66–0.82 <.001
 Overall (age and histology adjusted) 10 y 25521 4336 1250 0.71 0.64–0.80 <.001
 Anaplastic and GBM 5 y 783 481 387 0.70 0.57–0.85 <.001
 PNET and medulloblastoma 5 y 4650 1367 504 0.75 0.63–0.89 <.001
<3 y
 Pilocytic astrocytoma 10 y 2180 344 28 0.57 0.27–1.22 .146
 Anaplastic astrocytoma 10 y 127 32 14 0.52 0.19–1.48 .219
 Glioblastoma 10 y 68 28 19 1.07 0.43–2.67 .883
 Medulloblastoma 10 y 827 209 115 0.80 0.55–1.16 .234
 PNET 10 y 323 125 87 0.50 0.32–0.76 <.001
 Ependymoma 10 y 1067 218 96 0.82 0.55–1.23 .346
 Overall 10 y 4593 956 359 0.69 0.56–0.85 <.001
 Anaplastic and GBM 5 y 139 60 33 0.75 0.38–1.48 .400
 PNET and medulloblastoma 5 y 803 334 198 0.71 0.57–0.87 <.001
3–14 y
 Pilocytic astrocytoma 10 y 10754 1572 50 0.75 0.42–1.33 .325
 Anaplastic astrocytoma 10 y 432 186 152 0.83 0.60–1.14 .244
 Glioblastoma 10 y 358 235 209 0.68 0.51–0.89 .006
 Medulloblastoma 10 y 4637 808 254 0.84 0.66–1.08 .183
 PNET 10 y 1031 225 106 0.57 0.39–0.81 .004
 Ependymoma 10 y 1920 354 108 0.86 0.59–1.26 .446
 Overall 10 y 19132 3380 879 0.76 0.67–0.87 <.001
 Anaplastic and GBM 5 y 644 421 354 0.69 0.52–0.91 .009
 PNET and medulloblastoma 5 y 3848 1033 306 0.85 0.69–1.07 .163