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Activity of the compounds in an influenza virus plaque reduction assay. MDCK cells were infected with influenza virus (strain A/HK/7/87; 25 PFU per well) in the presence of the test compounds (concentrations, from left to right: 0.5, 2, and 8 μM). After 72 h incubation, plaques were visualized by crystal violet staining. VC: mock-treated virus control. CC: uninfected cell control.
