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Histologic characteristics of Panc-02 tumors based upon diet
| Normal diet | High-fat diet + vehicle | High-fat diet + antagonist | |
|---|---|---|---|
| Tumor inflammation | 2.00 ± 0.17 | 1.90 ± 0.28 | 1.56 ± 0.29 |
| % of tumors with vascular emboli | 33 | 33 | 0 |
| Inflammation in adjacent normal pancreas | 1.45 ± 0.25 | 1.83 ± 0.17 | 1.40 ± 0.40 |
| Tumor vascularity | 1.91 ± 0.09 | 1.80 ± 0.13 | 1.89 ± 0.20 |
CCK receptor antagonism completely prevented tumor emboli
