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. Author manuscript; available in PMC: 2014 Jul 14.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2013 Nov 7;34(1):26–33. doi: 10.1161/ATVBAHA.113.302355

Figure 1.

Figure 1

Adenoviral vectors encoding G5G8 (AdG5G8) increases biliary cholesterol and fecal neutral sterols in lean and obese mice. Obese (db/db) male mice and their lean littermates were administered a cocktail of AdG5G8 or empty virus and G8 (control). A, Hepatic expression of G5G8 was confirmed by immunob-lot analysis. # Appearance of nonspecific band that comigrates with immature G5. Calnexin (CNX) was used as a loading control. B and C, Biliary cholesterol concentrations and fecal neutral sterols were measured by gas chromatography-mass spectrometry (GC-MS). Data are mean±SEM (n=3). Horizontal lines terminating in vertical bars denote significant difference from control virus within genotype. *P<0.05, **P<0.01. SR-BI indicates class B, type 1 scavenger receptor.