The figure shows TGF-β1 and 2 mRNA levels in Achilles tendon (A) and TGF-β1, 2 and 3 mRNA levels in calf muscle (B). Mice with low GH/IGF-I activity (GHR−/−, grey bars, tendon: n=8, muscle: n=15) or high GH/IGF-I activity (bGH, black bars, tendon: n=7, muscle: n=14) are shown relative to control mice (CTRL, only error bars visible, tendon: n=12, muscle: n=24). All data are relative to GAPDH mRNA. Values are geometric mean ± back-transformed SEM (***p<0.001, only differences compared to control are shown).