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. 2014 May 8;197(3):823–838. doi: 10.1534/genetics.114.164814

Table 4. Significant associations.

Disease SNP ID Chr Region (Mb) Gene BF2 P2 BF1 P1
CAD rs7104543 11 120.16–120.24 GRIK4 7.29 10.74 0.71 2.36
RA rs1010342 4 1.04–1.08 SPON2 6.11 11.98 0.60 2.33
RA rs11218032 11 120.16–120.24 GRIK4 11.60 14.50 −0.90 0.52
T2D rs2383208 9 22.12–22.13 CDKN2A, CDKN2B 7.62 8.57 1.96 3.69
CD rs9268858 6 32.54–32.56 HLA-DRA 5.20 8.27 1.66 3.35
RA rs1605705 3 7.24–7.28 GRM7 5.76 8.43 1.04 2.82
T1D rs6578246 11 2.18–2.26 INS-IGF2 4.96 8.52 2.34 4.09
T1D rs3218256 22 35.87–35.87 IL2RB 4.60 6.47 2.44 4.26

P2 = −log10 P-value, which is the minimum P-value over 10 independent EM runs, and in each EM run a P-value was computed using logistic regression Equation 8. BF2 = log10 Bayes factor, which is averaged over 10 independent EM runs, and in each EM run a Bayes factor was computed using our haplotype method. P1 and BF1 are P-values and Bayes factors for the single-SNP test, respectively. The coordinates are from NCBI Build 35.