Table 1. Genes deregulated in the Ms2Yah mice hippocampi.

Group	Gene name	Chr	WT: mean ± SEM	Ms2Yah: mean ± SEM	FC	Test: posthoc
1	Cldn5	16	0.77 ± 0.15	0.52 ± 0.09	0.68	*
1	Cbs	17	0.9 ± 0.12	0.62 ± 0.05	0.69	*
1	Tmem234	4	0.84 ± 0.1	0.63 ± 0.07	0.75	*
1	Rps2	17	0.98 ± 0.08	0.74 ± 0.07	0.76	*
1	Fam40b/Strip2	6	0.95 ± 0.06	0.72 ± 0.08	0.76	*
1	Tek	4	0.85 ± 0.1	0.66 ± 0.14	0.77	**
1	Ggcx	6	0.99 ± 0.04	0.76 ± 0.09	0.77	*
1	Sox2	3	0.86 ± 0.11	0.67 ± 0.15	0.78	*
1	Hist1h1c	13	1.05 ± 0.15	0.82 ± 0.08	0.78	*
1	Hyou1	9	0.89 ± 0.08	0.69 ± 0.09	0.78	*
1	Copg	6	0.9 ± 0.07	0.7 ± 0.08	0.78	**
1	Slco1c1	6	0.95 ± 0.1	0.74 ± 0.12	0.79	*
1	Gm12696	4	0.71 ± 0.13	0.56 ± 0.12	0.79	*
1	Elk1	X	0.9 ± 0.08	0.71 ± 0.06	0.79	*
1	Gm11599	1	1.02 ± 0.07	0.8 ± 0.06	0.79	*
1	Spsb3	17	0.93 ± 0.04	0.73 ± 0.09	0.79	*
1	Slc39a1	3	1.04 ± 0.09	0.82 ± 0.15	0.79	*
1	2810006K23Rik	5	0.92 ± 0.06	0.73 ± 0.1	0.79	*
1	Tbl3	17	1.07 ± 0.12	0.85 ± 0.07	0.79	*
1	Msl3l2	10	0.96 ± 0.04	0.76 ± 0.12	0.8	*
1	Slc37a3	6	0.88 ± 0.05	0.7 ± 0.12	0.8	*
1	Smyd5	6	0.93 ± 0.09	0.74 ± 0.09	0.8	*
1	Hmcn1	1	0.87 ± 0.08	0.7 ± 0.09	0.8	***
1	Anapc1	2	0.97 ± 0.05	0.77 ± 0.17	0.8	*
2	Dlg1	16	0.87 ± 0.08	1.04 ± 0.1	1.2	*
2	Kcnn3	3	1.04 ± 0.05	1.25 ± 0.13	1.2	*
2	B430305J03Rik	3	1.08 ± 0.07	1.29 ± 0.1	1.2	*
2	Trp53inp1	4	1.12 ± 0.13	1.35 ± 0.15	1.2	*
2	Gdpd2	X	0.95 ± 0.04	1.14 ± 0.07	1.21	*
2	Gabrr2	4	1.28 ± 0.13	1.55 ± 0.09	1.21	*
2	Gm7820	X	1.09 ± 0.04	1.31 ± 0.12	1.21	*
2	Kitl	10	0.88 ± 0.07	1.06 ± 0.08	1.21	*
2	AI836003	15	1.05 ± 0.03	1.26 ± 0.1	1.21	*
2	Cav3	6	0.97 ± 0.04	1.17 ± 0.1	1.21	*
2	S100a10	3	0.91 ± 0.07	1.1 ± 0.1	1.21	*
2	Vma21	X	1.08 ± 0.15	1.31 ± 0.03	1.21	*
2	Figf	X	0.93 ± 0.15	1.13 ± 0.12	1.22	*
2	2210404J11Rik	17	0.98 ± 0.07	1.2 ± 0.13	1.23	*
2	Trhr	15	0.66 ± 0.14	0.81 ± 0.09	1.23	*
2	Tsc22d3	X	1.23 ± 0.26	1.52 ± 0.19	1.23	*
2	Gm4876	6	0.91 ± 0.09	1.12 ± 0.11	1.24	*
2	Arrdc2	8	1.19 ± 0.11	1.47 ± 0.21	1.24	*
2	Cpsf7	19	0.85 ± 0.11	1.06 ± 0.07	1.24	*
2	Cntn6	6	0.92 ± 0.08	1.14 ± 0.13	1.24	*
2	Dclre1b	3	1.05 ± 0.07	1.31 ± 0.16	1.25	**
2	Cacna1g	11	0.92 ± 0.06	1.16 ± 0.14	1.26	*
2	Huwe1	X	1.1 ± 0.11	1.39 ± 0.13	1.26	*
2	Fam70a	X	0.92 ± 0.09	1.16 ± 0.12	1.26	*
2	Gm129	3	1.12 ± 0.26	1.41 ± 0.24	1.26	*
2	Gabrr1	4	1.03 ± 0.05	1.31 ± 0.05	1.27	**
2	Gm9801	7	0.95 ± 0.08	1.21 ± 0.14	1.27	*
2	Anapc1	2	0.95 ± 0.15	1.2 ± 0.08	1.27	*
2	Thpo	16	1.03 ± 0.1	1.31 ± 0.1	1.27	*
2	Park2	17	1.21 ± 0.14	1.55 ± 0.08	1.28	**
2	Gm5148	3	0.96 ± 0.08	1.22 ± 0.13	1.28	*
2	Rnf7	9	0.96 ± 0.04	1.23 ± 0.13	1.28	*
2	Bmp2	2	0.99 ± 0.06	1.26 ± 0.17	1.28	*
2	Cit	5	0.92 ± 0.06	1.18 ± 0.09	1.28	*
2	Uevld	7	0.86 ± 0.07	1.11 ± 0.14	1.28	*
2	Usp54	14	1.12 ± 0.09	1.44 ± 0.25	1.29	*
2	Rnu1b1	3	1.01 ± 0.02	1.31 ± 0.09	1.29	**
2	1700048O20Rik	9	1.07 ± 0.03	1.39 ± 0.13	1.29	*
2	Brunol5	4	1 ± 0.11	1.3 ± 0.15	1.3	*
2	Eltd1	3	1.08 ± 0.12	1.42 ± 0.31	1.32	*
2	Carhsp1	16	1.06 ± 0.09	1.4 ± 0.17	1.32	*
2	Dhrs1	14	0.98 ± 0.12	1.31 ± 0.14	1.33	*
2	Mybl1	1	1.07 ± 0.11	1.44 ± 0.22	1.35	*
2	Dnahc3	7	0.98 ± 0.07	1.33 ± 0.25	1.36	*
2	Mir692-1	17	0.8 ± 0.14	1.09 ± 0.11	1.36	*
2	Gpr4	7	0.89 ± 0.09	1.22 ± 0.14	1.37	*
2	mIRNAAL589870	UN	1.08 ± 0.13	1.49 ± 0.16	1.37	**
2	Rin3	12	1.06 ± 0.04	1.48 ± 0.25	1.39	*
2	Camk2d	3	0.97 ± 0.06	1.36 ± 0.2	1.4	*
2	Erdr1	UN	1.13 ± 0.14	1.59 ± 0.07	1.41	*
2	Grid2ip	5	0.84 ± 0.08	1.19 ± 0.1	1.41	*
2	Taf1d	9	1.09 ± 0.17	1.56 ± 0.1	1.43	**
2	Ccl28	UN	0.81 ± 0.19	1.16 ± 0.1	1.44	*
2	Plekhf1	7	1.39 ± 0.25	2.05 ± 0.32	1.47	**
2	Meg3	12	0.85 ± 0.17	1.25 ± 0.15	1.48	*
2	3110052M02Rik	17	1.05 ± 0.16	1.59 ± 0.04	1.52	**

Groups of genes downregulated (1) or upregulated (2) for which the statistical test is <0.05 are listed. Chr, chromosome; FC, fold change. The posthoc statistical test used is a bilateral t-test. ***P < 0.001; **P < 0.01; *P < 0.05.