Table 3. Odds ratios for prevalent metabolic syndrome per quartile decrease of total testosterone, SHBG and free testosterone, stratified by age and BMI – results from cross-sectional studies.
OR (95% CI) | |||
Total testosterone | SHBG | Free testosterone | |
Body mass index | |||
<25 kg/m2 | N = 2377 | N = 1688 | N = 1688 |
1.43 (1.24–1.65) | 2.20 (1.77–2.72) | 1.22 (0.97–1.53) | |
25–30 kg/m2 | N = 3969 | N = 2714 | N = 2714 |
1.51 (1.40–1.62) | 1.50 (1.35–1.66) | 1.29 (1.16–1.44) | |
>30 kg/m2 | N = 1720 | N = 1145 | N = 1145 |
1.37 (1.24–1.51) | 1.33 (1.18–1.50) | 1.31 (1.15–1.50) | |
P interaction | 0.40 | 0.003 | 0.67 |
Age | |||
<40 years | N = 1080 | N = 875 | N = 875 |
1.87 (1.57–2.22) | 1.50 (1.22–1.84) | 1.57 (1.29–1.91) | |
40–60 years | N = 3985 | N = 3185 | N = 3185 |
1.78 (1.65–1.92) | 1.68 (1.54–1.83) | 1.52 (1.38–1.66) | |
≥60 years | N = 3029 | N = 1492 | N = 1492 |
1.54 (1.43–1.66) | 1.61 (1.43–1.82) | 1.32 (1.16–1.50) | |
P interaction | 0.004 | 0.11 | 0.01 |
Odds ratios are adjusted for age, smoking, alcohol consumption and physical activity. Abbreviations: SHBG = sex hormone-binding globulin; OR = odds ratio; CI = confidence interval.