Table 1.

Description of the common chemotherapy regimens used in the series

Platinum based regimens (name and dose)	Platinum free regimens (name and dose)
Cisplatin (100 mg/m2/3 weeks) + 5-FU (1000 mg/m2/d, 5 days/3 weeks)	Paclitaxel (60 to 80 mg/m2/week) + Cetuximab (400 mg/m2 then 250 mg/m2/week)
Cisplatin (75 mg/m2/3 weeks) + Docetaxel (75 mg/m2/3 weeks)	Paclitaxel (80 mg/m2/week)
Cisplatin (75 mg/m2/3 weeks) + Docetaxel (75 mg/m2/3 weeks) + Cetuximab (400 mg/m2 then 250 mg/m2/week)	Methotrexate (40 mg/m2/week)
Cisplatin (75 mg/m2/3 weeks) + Docetaxel (75 mg/m2/3 weeks) + 5-FU (750 mg/m2/d, 5 days/3 weeks)	Capecitabine (1,000 mg/m2 BID for 14 days/21 days)
Cisplatin (100 mg/m2/3 weeks) + 5-FU (1000 mg/m2/d, 4 days/3 weeks) + Cetuximab (400 mg/m2 then 250 mg/m2/week)
Carboplatin (AUC5/3 weeks) + 5-FU (1000 mg/m2/d, 4 days/3 weeks) + Cetuximab (400 mg/m2 then 250 mg/m2/week)
Carboplatin (AUC5/3 weeks) + Paclitaxel (80 mg/m2/week)
Carboplatin (AUC5/3 weeks)

5-FU = 5-Fluorouracil.

AUC = Area Under the Curve.