Table 3. Summary of NFT and NT density by clinical diagnosis.
| NCI (N=6) |
MCI (N=6) |
AD (N=6) |
p-value | Pair-wise comparison | ||
|---|---|---|---|---|---|---|
| AT8 NFT | Median (Range)* |
0 (0-0.88) |
0.46 (0-1.97) |
0.58 (0.34-2.00) |
0.091a | -- |
| TOC-1 NFT | Median (Range)* |
0 (0-0.96) |
0.51 (0-2.17) |
0.53 (0-1.95) |
0.6a | -- |
| Tau C3 NFT | # Absent | 6 | 4 | 4 | 0.5b | -- |
| # Present | 0 | 2 | 2 | |||
|
| ||||||
| AT8 NT | Median (Range)* |
1.92 (0-3.88) |
3.8 (1.34-5.96) |
4.54 (4.03-5.89) |
0.016a | NCI < AD |
| TOC-1 NT | Median (Range)* |
0.79 (0-4.19) |
3.64 (0-6.40) |
3.36 (1.10-4.89) |
0. 6a | -- |
| Tau C3 NT | Median (Range)* |
0.91 (0-1.44) |
0.24 (0-5.86) |
1.70 (0.88-4.73) |
0.2a | -- |
*
Based on log-transformed NFT and NT density values (number/mm2).
a
Kruskal-Wallis test, with Dunn's correction for multiple comparisons.
b
Fisher's exact test.