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. 2014 Jul 9;9:3263–3277. doi: 10.2147/IJN.S63095

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© 2014 Plencner et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Metabolic activity of 3T3 fibroblasts cultivated on the surface of PP mesh, PP mesh functionalized with PCL nanofibers (PP + PCL), PCL nanofibers, and TCP. MTT assay revealed significantly higher viability of 3T3 fibroblasts on the PP + PCL and PCL scaffolds on days 1, 3, 7, and 10 (indicated by asterisks) compared with scaffolds without functionalization (PP).

Notes: The level of statistical significance for the assays is designated above the mean values (P<0.05 indicated by number, P<0.001 indicated by number and asterisks). Day 1: 2>1; 3>1; 4>1*, 2*, 3*. Day 3: 2>1; 3>1; 4>1*, 2*, 3*. Day 7: 2>1*; 3>1; 4>1*, 2*, 3*. Day 10: 2>1*; 3*>1; 4>1*, 2*, 3*.

Abbreviations: PP, polypropylene; PCL, poly-ε-caprolactone; TCP, tissue-culture polystyrene; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide.