Risk of dementia and subtypes Alzheimer’s (AD), vascular (VaD) and mixed dementia, by level of Lp-PLA2 mass and activity in fully adjusted models*; hazard ratios and 95% confidence intervals are shown comparing the highest to lowest quartile.
* Models adjusted for age, race, gender, years of education, history of hypertension, diabetes, CHD, stroke, smoking status, pack years of cigarettes smoked, body mass index, alcohol use, common carotid intima medial thickness (IMT), internal carotid IMT, C-reactive protein, Interleukin 6, total and LDL cholesterol, triglycerides, use of lipid-lowering drug, and ApoE genotype.