Figure 5. Effect of H1-antihistamines on the expression of COX1, COX2, iNOS, eNOS and Egr1 mRNA in aorta.
Aortic tissues harvested from three or four mice from each group were analyzed for mRNA expression by qRT-PCR. Each gene amplicon was normalized for the β-actin expression. Placebo (Pl), cetirizine low (C.L), cetirizine high (C.H), fexofenadine low (F.L) and fexofenadine high (F.H). Data presented are mean ± SEM of the fold change compared to control values. *p<0.05 vs. controls.